Abstract

In-vitro Antiproliferative Activity Study of 2, 4, 5-Triphenyl-1H-imidazole Derivatives

Various substituted 2, 4, 5-triphenyl-1H-imidazole derivatives were synthesized and evaluated for in vitro antiproliferative activity against human non-small cell lung carcinoma-A549 cell lines by MTT assay method. Compound 2-iodo-6- methoxy-4-(4, 5-diphenyl-1H-imidazol-2-yl) phenol (6f) (IC50: 15 μM) was found to be most promising which inhibits the growth of cancer cells (90.33% of total population).

image


Author(s):

Satish A Dake, Kiran R Kharat, Ashok R Yadav, Pravin S Kendrekar and Rajendra P Pawar



Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+

paper.io

agar io

wowcappadocia.com
cappadocia-hotels.com
caruscappadocia.com
brothersballoon.com
balloon-rides.net

wormax io